Transform extracted teeth into a highly effective autogenous bone graft.

Dentin-derived bone grafts provide growth factors* plus the mineral structure to support osteoconduction.  The KometaBio Dentin Processor is used in conjunction with a Kometabio consumables kit (sterile blade, pots and cleaning solutions) to create a patient-specific graft providing:  

• Osteoinductive, growth factor and BMP-rich performance.   

  • Dentin graft processed with KometaBio contains type 1 Collagen plus growth factors (BMP-2 & TGF) – just like bone.

  • Up to 63% vital new bone.

  • Direct (Ankylosis) shown by histology. (See attached)High patient engagement and acceptance. 

• High patient engagement and acceptance.

  • Recycling their extracted teeth stimulates patients and creates a more receptive discussion when implant restoration is discussed. 

• Cost-effective efficiency. 

  • One tooth can generate up to 2.0cc of graft at a consumable cost of £23 per cc. (+vat for UK sales)

Winner of the ‘Most Innovative Product Award’ at the French Dental Association Conference 2014.

KOMETABIO INDICATIONS

Dentin-processed bone graft is suitable for multiple indications such as: 

• Ridge Preservation. (AKA Socket Preservation)

Teeth recycled using KometaBio offer a high-density graft ideal for long-term volume preservation when placed in a freshly extracted and degranulated socket.

• Immediate Placement Defects.

Use the osteoinductive stem cell and growth factors alone or as supplements to fully resorbable particulates such as or Powerbone Granules.

• Sticky Bone.

Combine KometaBio-prepared Dentin with a freshly prepared PRF membrane (slug) to create an osteoinductive sticky bone graft. (See separate protocol)

• Ridge Augmentation.

Combine KometaBio prepared Dentin Dentin graft with a fully resorbing bioactive synthetic such as Powerbone Resorbing Granules or Powerbone Flexible graft for an onlay or inlay procedure. For grafting outside the bone envelope consider combining with slowly resorbing HA-based Ti-oss (xenograft) or Powerbone Biphasic (synthetic).

PROCESSING INSTRUCTIONS

Step-by-step tutorial on using the KometaBio ‘Genesis’ kit to create a patient-specific autologous graft from an extracted molar. 

EDUCATION AND ONLINE LECTURE – Dr Bob Horowitz

• Link here.

EXTENSIVE EVIDENCE

Histology slides

DOWNLOADS

• Spec Sheet and FAQ: KometaBio Dentin Derived Protocol_Regen Store_Jan 2024

• Tips and Tricks: KometaBio_10 tips and tricks_Apr22

• Sticky Bone: Sticky Bone Protocol_Regen Store_Sept20 

• Sticky Bone Video: Video link to youtube

• Dentin Storage: KometaBio_Saving protocol_Regen Store_APR22_V2

• Case Studies: KometaBio – Cases book-FINAL

• Case Study: Dr Fahd Saleh_Kometabio

• Publications list: https://www.kometabio.com/scientific-publications

COMPANION PRODUCTS

KometaBio Consumable Kit

KometaBio Graft Accelerator Kit

*Refs:

Murata, M. Bone engineering using human demineralized dentin matrix and recombinant human BMP-2. J. Hard Tissue Biol. 2005, 14, 80–81.

Bernardi, S.; Macchiarelli, G.; Bianchi, S. Autologous materials in regenerative dentistry: Harvested bone, platelet concentrates and dentin derivates. Molecules 2020, 25, 5330.

Roberts-Clark, D.; Smith, A.J. Angiogenic growth factors in human dentine matrix. Arch. Oral Biol. 2000, 45, 1013–1016.

Tooth Grinder Dentin Grinder