Ti-oss Guide collagen membrane. More membrane, longer function,¹ less money ²

MATERIAL
Ti-oss Guide is a 15 x 30mm dental barrier membrane composed of Type-1 porcine collagen with:

• Easy handling: Excellent tensile strength, fast hydration and high tear resistance – wet or dry.  

• Extended barrier function:  Compared to native collagen membrane (Bio-Gide) with a minimum function barrier time of 12 weeks¹

• Excellent economy: More membrane (15 x 30mm) for less cost compared to 1st generation alternatives^2/3

EXTENDED BARRIER FUNCTION

Despite significant evidence supporting collagen membranes in GBR, users frequently report premature degradation. This limitation of 1st generation materials and the corresponding reduced barrier function led developers to seek methods to prolong degradation time and increase functional performance.  One example is cross-linking which enhances the durability and mechanical properties of collagen and broadens the predictability of applications (1).

A variety of cross-linking techniques exist with one being the addition of EDC.

Collagen membranes like Ti-oss Guide with EDC cross-linking present favourable structural durability at 8 weeks and greater new bone formation with the support of bone substitute material compared to the membrane alone and bone substitute alone [22]. In a dog model, {EDC cross-linked} membranes contributed to higher and long-lasting osteogenic activity, evaluated by immunohistochemical assay [23] compared to two widely used alternatives (A&B).

BONE GRAFT OPTIONS

Select your bone graft according to origin, form and resorption profile. Select your ideal characteristics HERE.

References
1.Rothamel D., Schwarz F., Sager M., Herten M., Sculean A., Becker J. Biodegradation of differently cross-linked collagen membranes: An experimental study in the rat. Clin. Oral Implant. Res. 2005;16:369–378. 
2.Ti-oss Guide 15 x 30mm (450mm3) = £0.15 / mm3.  T-Gen Collagen 15mm x 20mm (300mm3) = £0.22 / mm3.  Geistlich Bio-Gide 25 x 25mm (625mm3) at £129.86 = £0.21 per mm3. {equivalent to £93.15 for 450 cc3} 
and Geistlich Bio-Gide 30 x 40mm (1240mm3) at £209.94 = £0.17 per cc3 (Wrights, March 2024)

Powerbone Resorbing Fixation Tacks are used to secure biodegradable Dental Membranes to the bone bed.  The use of Powerbone Resorbing Fixation Tacks with a biodegradable membrane allows a true one-step GTR or GBR procedure.

2 x 4mm x 2mm tacks.

INDICATIONS

Use with a slow-resorbing or fully resorbing bone graft for periodontal defects (e.g. class II furcation defects, intra-bony and recession-type defects) and for peri-implant surgery, GBR bony defects, and to cover an empty socket in conjunction with a particulate bone graft or biphasic socket sponge graft.

FIXATION

Use the Powerbone Dental Membrane Fixation tool as shown. HERE.

RESORBING DENTAL MEMBRANES

Fully Resorbing Dental Membranes are available in single or double-layer forms. 

Titanium Fixation Screws can be found HERE. 

Powerbone rESORBING Fixation Tacks are CE-marked medical devices.

Save £26 (16%) compared to Geistlich* and get More Bone and More Membrane.

SUMMARY OF PRODUCT CHARACTERISTICS

SPECIFIC INFORMATION for Ti-oss bone Here  / SPECIFIC INFORMATION for Ti-oss Guide Here

*Geistlich Combi Kit Collagen (GE10013) is £164.98 in Wright Dental Catalogue. Feb 2024.
*Bi-oss is a registered trade mark of Geistlich Biomaterials, Wolhusen, Switzerland and used here for comparison purposes only. 

MATERIAL
Ti-oss Guide is a 15 x 30mm dental barrier membrane composed of Type-1 porcine collagen with:

• Easy handling: Excellent tensile strength, fast hydration and high tear resistance – wet or dry.  

• Extended barrier function:  Compared to native collagen membrane (Bio-Gide) with a minimum function barrier time of 12 weeks¹

• Excellent economy: More membrane (15 x 30mm) for less cost compared to 1st generation alternatives^2/3

EXTENDED BARRIER FUNCTION

Despite significant evidence supporting collagen membranes in GBR, users frequently report premature degradation. This limitation of 1st generation materials and the corresponding reduced barrier function led developers to seek methods to prolong degradation time and increase functional performance.  One example is cross-linking which enhances the durability and mechanical properties of collagen and broadens the predictability of applications (1).

A variety of cross-linking techniques exist with one being the addition of EDC.

Collagen membranes like Ti-oss Guide with EDC cross-linking present favourable structural durability at 8 weeks and greater new bone formation with the support of bone substitute material compared to the membrane alone and bone substitute alone [22]. In a dog model, {EDC cross-linked} membranes contributed to higher and long-lasting osteogenic activity, evaluated by immunohistochemical assay [23] compared to two widely used alternatives (A&B).

BONE GRAFT OPTIONS

Select your bone graft according to origin, form and resorption profile. Select your ideal characteristics HERE.

References
1.Rothamel D., Schwarz F., Sager M., Herten M., Sculean A., Becker J. Biodegradation of differently cross-linked collagen membranes: An experimental study in the rat. Clin. Oral Implant. Res. 2005;16:369–378. 
2.Ti-oss Guide 15 x 30mm (450mm3) = £0.15 / mm3.  T-Gen Collagen 15mm x 20mm (300mm3) = £0.22 / mm3.  Geistlich Bio-Gide 25 x 25mm (625mm3) at £129.86 = £0.21 per mm3. {equivalent to £93.15 for 450 cc3} 
and Geistlich Bio-Gide 30 x 40mm (1240mm3) at £209.94 = £0.17 per cc3 (Wrights, March 2024)

A pack of 5 micro threaded screws with Philipps cross head suitable for fixation of dental barrier membranes and other thin biomaterial devices. These are threaded screws – not a standard ‘push-in’ ‘tack’ (see below).   The screw head is precision made for one-handed application using a compatible Phillips head motor driver or hand driver.

NOTE:  Standard ‘push-to-fit’ membrane ‘tacks’ can be purchased HERE.   

Fixation Screw is recommended for stable fixation of:

Resorbable Dental Barrier Membranes such as:

• Powerbone Resorbable Polymer Membrane

• Tis-oss GUIDE Resorbable Collagen Membrane.

• Powerbone 2mm Flexible Graft when used for onlay GBR.

Non-Resorbable Dental Barrier Membranes such as:

• Ultra-Thin Titanium Mesh 

*Some images for illustration purposes. The final product may differ slightly in colour or thread orientation.

Hydrophilic, Porous and Cell-free, this fully adsorbing coated implant helps regenerate articular cartilage in knee, ankle, or hip.

25 x 25 x 1.1mm

FEATURES 

• Non-woven polymer matrix created by the Jet-Spray Technique.

• Easily cut without fragmentation.

• Sodium Hyaluronate Coating.

Provides structural support for 4 to 6 months.

• Unlike collagen alternatives, Chondro Matrix contains no animal or human tissue.

INDICATIONS

• Cartilage repair and the surgical treatment of pain and restricted mobility in degenerative and traumatic changes of the synovial joints.

• Intra-articular haemostasis and to protect underlying tissue when there is pain and restricted movement in cases of degenerative and traumatic changes in the synovial joints. 

CONTRAINDICATIONS

• Known allergies to one of the constituents.

• Do not implant Chondro Matrix directly into the bloodstream.

• Patients who have to undergo chemotherapy and/or radiotherapy up to three weeks after the implant.

• Children or pregnant and lactating women, or patients with inflammatory joint diseases, such as rheumatoid arthritis and Bechterew‘s disease.

SCIENCE

Chondro Matrix is a high-tech, sterile, absorbable matrix with sponge-like characteristics.  The non-woven Polymer strands are treated with Sodium Hyaluronate to aid in the healing of articular cartilage damage within a bone-marrow stimulating technique.  Chondro Matrix is a cell-free implant for joint cartilage repair and used for cartilage repair and for the surgical treatment of pain and restricted mobility in degenerative and traumatic changes of the synovial joints.

Chondro Matrix is intended to cover traumatic cartilage defects in the healing of articular cartilage defects. The compact layer with a smooth surface plays the role of a barrier, preventing the mesenchymal stem cells from diffusing into the joint space and protecting them against mechanical stress.  Chondro Matrix induces mesenchymal progenitor cells (stem cells) to differentiate into cartilage cells.

DEGRADATION

The polymer of Chondro Matrix is metabolised by the body into CO2 and H2O. 

MORE INFO ask@regen-store.co.uk to learn more or to discuss a suitable case.

The stability of dental bone grafts and supporting barriers is critical for undisturbed regeneration. 

VIDEO DEMO

https://youtu.be/jMcayKmgZ9s

RELATED PRODUCTS

Membrane Tack Kit by Powerbone

*Box supplied separately.

CONTENTS

• Titanium Hand Applicator.

• Autoclavable screw top box with 20 barbed titanium membrane tacks. 

Suitable for Fixation of: 

• Collagen (Resorbable) Membrane.

• Powerbone Synthetic (Resorbable Membrane)

• PTFE (Non-Resorbable) Membrane 

• Ultra-Thin Titanium Mesh.

This applicator is also used to fix the NEW Powerbone Adsorbing Fixation Tacks.

VIDEO DEMO

*UPGRADE OPTIPON

Need a tack removal tool? Upgrade to the Dental Studio Tack fixation and Removal Kit for + £100.  HERE.

RELATED PRODUCTS

Titanium Membrane Tacks

Resorbable Polymer Membrane Tacks.

Available in Single Layer or Double Layer format.

Thermo-moldable synthetic polymer membranes can be shaped when warm, increasing the defect conformity. Unlike collagen, Powerbone Dental Membrane offers:

• Excellent Space Creation.

• Long barrier function time – 12–16 weeks. 

• Resilience to exposure – Polymer is not degraded by salivary enzymes.

• No uncomfortable patient conversation about animal or human tissue.

• No need for a second procedure to remove, unlike PTFE or Titanium. 

AVAILABLE IN SINGLE-LAYER* OR DOUBLE-LAYER VERSIONS**

• Small – 15 x 20mm (Single or Double)

• Medium – 20 x 30mm (Single or Double)

• Large – 30 x 40mm (Single or Double)

COMPARISON WITH COLLAGEN – Single Layer format

Clinicians familiar with resorbing collagen membranes will readily appreciate the single-layer synthetic polymer membrane.  The single-layer version drapes more easily. Fixation with pins or membrane tacks is advisable, yet not mandatory. 

COMPARISON WITH PTFE – Double Layer format

Clinicians familiar with PTFE will appreciate the double-layer synthetic polymer membrane.  The double layer holds the space very well. It is more rigid than the single layer, and as such fixation is mandatory.  Unlike PTFE Powerbone Synthetic Polymer membrane resorbs completely and does not require a second procedure for removal. 

COMPARISON GUIDE: Refresh the key variances before integrating resorbable polymer into your treatment kit. Download our transition guide.

Adsorbing Barrier Membranes Compared_Regen Store_MAY25

*The Single-Layer product is branded Ecobone. ** The Double Layer Product is Branded Powerbone. Both are from the same manufacturer.

LINKED PRODUCTS

Powerbone Membrane Tack System

Dental Studio Bone and Membrane Fixation System

• Handling: Excellent tensile strength, fast hydration and high tear resistance – wet or dry, any side up.  

• Barrier Function:  c50% greater than type BG at 12–16 weeks.

• Tissue Integration: c20% greater than type BG due to higher porosity and surface area.

CASE STUDIES

Fenestration Defects, Dehiscence Defects, Ridge Preservation and Sinus Perforation Repair:

DOWNLOAD SPEC SHEET

T-Gen Collagen Membrane_Regen Store_Oct20

BONE GRAFT OPTIONS:

Regen store provides bone grafts according to their origin, form and resorption profile. Select your ideal characteristics HERE.