Newer techniques for the processing of bone graft materials bring significant clinical benefits to clinicians experienced with using traditional HA-based xenograft materials.
One such material is Ti-oss OCP-rich xenograft.
What is Ti-oss?
Ti-oss is a highly porous bone graft scaffold derived from 100% cancellous bone of bovine origin. Unlike traditional xenografts and some mineralised allografts, Ti-oss is prepared using a low-temperature process, which retains greater porosity. The process includes a surface treatment with an OCP-rich surface shown to stimulate osteoblastic activity. Moreover, the advanced processing ensures an average pore size 3 x that of Bio-Oss, which enhances the economic benefits due to greater defect fill per gram as shown in the included image.
OCP or octa calcium phosphate has the chemical structure Ca8H2(PO4)65H2O. Numerous studies confirm that OCP enhances bone regeneration due to osteoblast stimulation during the conversion of OCP into HA and thus induces new bone deposition. This initial step is followed by collagen formation, apatite crystal deposition, and bone mineralisation. (1)
OCP and Ti-Oss Histology.
Osteoblasts are directly aligned on the OCP and the newly formed osteoid bone matrix. Osteoblasts are cuboidal, indicating that active synthesis of bone matrix collagen is occurring.
An osteoclast cell is seen in contact with osteoblasts and attached directly to the OCP surface, suggesting active resorption. B: newly formed bone. * OCP granule. Osteoclasts arrowed. (1)
More about Ti-Oss OCP-rich xenograft and the long-term human studies supporting its predictable performance can be accessed here.
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Always active
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
