Ti-oss Xenograft Bone

Ti-oss xenograft delivers Predictable Long-Term Results.

10-year documentation shows Ti-oss delivers more bone than Bio-oss¹ – at a lower cost².

BUY 3 GET 1 FREE

TI-OSS – THREE KEY DIFFERENTIATORS CREATE CLINICAL BENEFIT 

PORE SIZE AND DENSITY

Ti-oss uses only the cancellous portion, which is more porous and less dense than grafts containing cortical parts, such as Bio-oss and many processed allograft mixes.

->High porosity is a prerequisite to clot adsorption and blood penetration.   

->High Porosity means less graft is needed. 1.0g of Ti-oss is equivalent to 2.3cc. By comparison, 1g of Bio-Oss standard particle is equivalent to 2cc.

SURFACE PROPERTIES

Ti-oss is created with an Octa Calcium Phosphate hydrophilic surface coating, shown to:  

-> Have a positive effect on the osteoinductive properties of biomaterials and encourage fast bone formation’

-> Enhance clot adhesion and improve osteoblast retention compared to alternatives.  

OCP bio-activity paper_Ti-Oss | OCP inductive study

PROCESSING.

All xenograft (animal) and allograft (another human) tissue must be processed to make them safe for use. Traditional processing uses high heat, which creates a denser, more crystalline material that the body is less able to remodel. Consequently, it treats the particle as a foreign body and often encapsulates remaining remnants in fibrous tissue. 

Tio-Oss is processed with mid-level temperature, supplemented by chemical treatment, resulting in a higher percentage of material the body can replace rather than one.

-> 15% graft remnants v 35% for Bio-Oss (Yoona Jung / Valentin, JOMI 2018. 33 (6) @1345=1350) 

->Superior bone fill and bone density compared to Allograft (DFDBA –Najeeb and co-workers)

LATEST CASES & CLINICAL NEWSLETTERS

OCP coating has a positive effect on the osteoinductivity of biomaterials_2026.07_38

2026.05_News 36_Case_Dr. L C. Arenaza Leal_Achieving Reliable and Predictable GBR Outcomes in the Esthetic zone. LOW RES

Ti-oss_Horizontal & Vertical Augmentation_47 months follow-up. 2026.04_Ed 35

Newsletter 34_Ti-oss in Bilateral Sinus at 36 months_Mar26

1_updated_2025.11_Edition 30_Dr. Lina C. Arenaza Leal_Predictable GBR in the Esthetic Zone (1)

STUDY LIBRARY: https://www.ti-oss.com/research-and-articles

STUDY TITLES:

• Human Sinus Bone Formation Study, Human Cyst.   Cavity Bone Formation Study, ​Rabbit Tibia.  12-Week Study Mouse Calvarial Defect Study.
• Jee-Ho Lee. Bone Regeneration of Macropore Octacalcium Phosphate–Coated Deproteinized Bovine Bone Materials in Sinus Augmentation: A Prospective Pilot Study.
• Rabbit Tibia 12 Weeks Comparison Study between Ti-oss® (Chiyewon Co.) & OCSB® (Nibec Co.).
• Clinical Report: Sinus Lift (Socket Lift), Vertical & Horizontal Augmentation. Histomorphometric Study on Healing of Critical Sized Defect in Rat Calvaria Using Two Different Bovine Grafts.
• Comparison of Ti-oss® & Bio-oss® in New Bone Formation on Rat Calvarial Defect in 8 Weeks.
• Bone Regeneration of Macropore Octacalcium Phosphate–Coated Deproteinized Bovine Bone Materials in Sinus Augmentation: A Prospective Pilot Study.
• Ti-oss® Resorption by Osteoclasts Found in an 8-Week Rat Model.
• Solution for Sinus Membrane Tear Using PRP & Ti-oss® Bone Graft in One-stage Approach.
• Socket grafting using a large particulate Xenograft as a prelude to implant placement: A case report and histology.
• Evaluation of New Octacalcium Phosphate-Coated Xenograft in Rats Calvarial Defect Model on Bone Regeneration. Yoona Jung.
• Three-Dimensional Radiographic Bone Fill Evaluation Using Octacalcium Phosphate-Coated Deproteinized Bovine Bone Material (Ti-Oss Bone Graft) and Demineralised Freeze-Dried Bone Allograft (DFDBA) in Three-Walled Defects.
  Immediate Loading Post-extraction Implant in the Aesthetic Region Following Trauma.
• Horizontal and Vertical Ridge Augmentation in the Esthetic Zone.
• Immediate Loading with Many Complicated Factors (severe periodontal disease, collapsed occlusion, Immediate extraction).
• Guided bone regeneration procedure for implant placement in the esthetic zone: A Case Report. A Rare Case Report of Idiopathic Infected Radicular Cyst.
• Brand comparisons: Ti-oss & Bio-Oss in new bone formation, Jun, Sangho, Korea University Oral Maxillofacial Dept. Ti-oss and OCSB (Nibec co), Yonsei University, Seoul, Korea.

* Bi-Oss is a registered trademark of Geistlich Biomaterials, Wolhusen, Switzerland and is used here for reference and comparison purposes only.

1. Lee and co-workers. Calvarial defects – Ti-oss, complete bone infill, Bio-Oss partial bone infill.
2. Pricing comparison: Geistlich Bio-Oss Granules 0.25- 1 mm 0.5 g at £88.73 (ex. VAT). BF Mulholland (NI) website (June 2023).